1/1

Vivostat PRF®

 
New Generation Autologus Platelet Rich Fibrin
 
Unique combination of fibrin and platelets
 
Healing the natural way
What is PRF


 

A revolution in tissue regeneration!

Growth factors and fibrin are essential components when it comes to regeneration of tissue. Using the Vivostat® system, you can prepare autologous platelets with multiple growth factors embedded in a fibrin sealant matrix. From 120 ml blood, 5-6 ml of Platelet Rich Fibrin (PRF®) is prepared. By combining a platelet concentrate with a fibrin sealant solution, it is possible to have a carrier, a controlled release and a medium for vascular ingrowth – all in one product, Vivostat PRF®.

Compared to conventional PRP products, Vivostat PRF® has a number of advantages.


Combining the benefits of platelets and fibrin
With an average 7-fold increase over baseline blood levels, the platelet concentration in Vivostat PRF® exceeds the baseline platelet count of 1 million/μL, which has become a benchmark within platelet therapy. The fibrin matrix ensures a slow release of growth factors over time and effectively protects the growth factors against proteolytic degradation.


Superior application performance
The specially designed Vivostat® Spraypen® and the unique combination of platelets and fibrin ensures easy, accurate and efficient application of Vivostat PRF®. Due to instant polymerisation and excellent adhesive properties of the fibrin component, the PRF® solution remains where it is applied - even when applied on vertical or inverted surfaces. As the fibrin component in Vivostat PRF® is based on a fibrin 1 solution, there is no need to use a separate thrombin component.


Naturally utilising the combination of platelets and fibrin sealant has many more benefits. These are described under the section 

1/1
Product characteristics
 

Clinical studies have demonstrated the beneficial effect of combining a platelet concentrate with a high concentration of fibrin. The Vivostat® system is the first and only system on the market to offer a convenient and fully automated process for the preparation of a platelet rich fibrin (PRF®).

Vivostat PRF® contains a variety of potent growth factors that stimulate fibroblast proliferation and tissue synthesis, e.g. TGF-β1,PDGF, VEGF, FGF-2 etc. Several in-vitro investigations confirm the unique characteristics of Vivostat PRF® and its ability to stimulate cell growth.